Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 8/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640341 | 0.81 | PTPRZ1 (0.37) | PTPRZ1USP2MAPTTSHRPTPRC | |
| SCHEMBL506786 | 0.81 | MAOB (0.53) | MAOB | |
| SCHEMBL8560939 | 0.78 | HTT (0.48) | PTPRZ1USP2MAPTTSHRPTPRC | |
| SCHEMBL2566681 | 0.76 | MAOB (0.49) | USP2MAPTTSHRAPPMAOB | |
| SCHEMBL9578594 | 0.76 | LTA4H (0.44) | USP2MAPTTSHRAPP | |
| SCHEMBL7762488 | 0.76 | KDM4E (0.41) | USP2MAPTTSHRAPPMAOB | |
| SCHEMBL10178017 | 0.76 | DRD2 (0.41) | MAPTMAOB | |
| SCHEMBL3032947 | 0.76 | ALDH1A1 (0.45) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9578562 | 0.74 | PKM (0.53) | USP2MAPTTSHRNPC1RAB9A | |
| SCHEMBL506251 | 0.73 | MAOB (0.46) | MAPTMAOBMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866793-A4 | — | — | 1998-10-07 | — | — | EP | disclosed |
| EP-0866793-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997001562-A1 | NITROIMIDAZOLE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |