Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20854051 | 0.85 | CSNK1E (0.48) | CNR2CTSKCSNK1EMMP1MMP9 | |
| SCHEMBL27666824 | 0.79 | CTSK (0.49) | CNR2CTSKMMP1MMP9MMP13 | |
| SCHEMBL20854105 | 0.79 | CSNK1E (0.45) | CNR2CTSKCSNK1EMMP1MMP9 | |
| SCHEMBL20853957 | 0.79 | CSNK1E (0.45) | CNR2CTSKCSNK1EMMP1MMP9 | |
| SCHEMBL3268589 | 0.77 | HIF1A (0.50) | CTSKALDH1A1TRPA1SMN1; SMN2HIF1A | |
| SCHEMBL5878905 | 0.76 | ACE2 (0.46) | — | |
| SCHEMBL5879066 | 0.76 | ACE2 (0.46) | — | |
| SCHEMBL29270029 | 0.76 | ACE2 (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL9800685 | 0.76 | CSNK1E (0.50) | CNR2CTSKCSNK1EMMP1MMP9 | |
| SCHEMBL2788441 | 0.76 | CSNK1E (0.47) | CNR2CTSKCSNK1EMMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1737-H | 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5512690-A | 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-basopastic compounds and method for preparing same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-30 | — | — | US | disclosed |