Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682671 | 0.95 | — | — | |
| Alcohol SCHEMBL28241942 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRPAOXACHELMNA | |
| SCHEMBL1520914 | 0.87 | — | — | |
| SCHEMBL2751863 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRPAOXACHELMNA | |
| SCHEMBL11780727 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRPAOXACHELMNA | |
| SCHEMBL8105099 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRPAOXACHELMNA | |
| SCHEMBL25754078 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRPAOXACHELMNA | |
| SCHEMBL8464714 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRPAOXACHELMNA | |
| SCHEMBL27099561 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRPAOXACHELMNA | |
| SCHEMBL13619946 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRPAOXACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5775329-A | DERIVATIVES OF NOREPINEPHRINE USED TO STIMULATE EXERCISE STRESS AND ITS EFFECTS ON THE HEART. | GENSIA, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0833816-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040621-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1996-12-19 | — | — | WO | disclosed |