Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561679 | 0.92 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8562781 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8565790 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8562433 | 0.86 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8568437 | 0.84 | PPARG (0.57) | PPARG | |
| SCHEMBL8559291 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL7299126 | 0.81 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL8563799 | 0.81 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8565793 | 0.79 | AGTR1 (0.51) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL8568424 | 0.78 | AGTR1 (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603001-B1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0603001-A1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO COMPANY LIMITED (JP) | 1994-06-22 | — | — | EP | disclosed |