Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666647 | 0.88 | SNCA (0.59) | SNCARAB9AKMT2ATP53POLB | |
| SCHEMBL8559221 | 0.85 | HDAC1 (0.61) | TP53HTTL3MBTL1KDM4EHDAC1 | |
| SCHEMBL6976656 | 0.81 | SNCA (0.63) | SNCARAB9AHTTGAAL3MBTL1 | |
| SCHEMBL27833525 | 0.80 | SNCA (0.58) | SNCARAB9AKMT2ATP53NPSR1 | |
| SCHEMBL7660277 | 0.77 | GAA (0.43) | SNCAPOLBGAAKDM4EHDAC1 | |
| SCHEMBL7663121 | 0.77 | MAPK1 (0.53) | RAB9AKMT2ANPSR1HSD17B10GAA | |
| SCHEMBL7670435 | 0.76 | SNCA (0.41) | SNCARAB9AKMT2AHDAC1NPC1 | |
| SCHEMBL7659463 | 0.76 | SNCA (0.41) | SNCAHDAC1HDAC2 | |
| SCHEMBL6643468 | 0.76 | CYP2C19 (0.54) | SNCARAB9AKMT2AHSD17B10HTT | |
| SCHEMBL11776962 | 0.75 | RAB9A (0.62) | RAB9AKMT2ATP53NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |