Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595391 | 0.78 | LMNA (0.51) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL8562051 | 0.73 | LMNA (0.46) | LMNACYP2C19HIF1A | |
| SCHEMBL7596337 | 0.73 | LMNA (0.48) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL9735781 | 0.72 | LMNA (0.60) | LMNACYP2C19HIF1AMAP2K1 | |
| Iomeprol SCHEMBL26981 | 0.72 | LMNA (0.63) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL9737493 | 0.71 | LMNA (0.77) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL9736495 | 0.70 | LMNA (0.60) | LMNACYP2C19HIF1AMAP2K1 | |
| Ioversol SCHEMBL24711 | 0.70 | LMNA (0.64) | LMNACYP2C19HIF1AMAP2K1 | |
| Ioversol SCHEMBL9745016 | 0.70 | LMNA (0.64) | LMNACYP2C19HIF1AMAP2K1 | |
| SCHEMBL11296490 | 0.70 | LMNA (0.64) | LMNACYP2C19HIF1AMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782564-B1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-09-01 | — | — | EP | disclosed |