Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625079 | 0.95 | — | — | |
| SCHEMBL14141227 | 0.85 | PAOX (0.52) | ALDH1A1PAOXACHEFOLH1LMNA | |
| SCHEMBL20029454 | 0.85 | PAOX (0.52) | ALDH1A1PAOXACHEFOLH1LMNA | |
| SCHEMBL12592611 | 0.85 | PAOX (0.52) | ALDH1A1PAOXACHEFOLH1LMNA | |
| SCHEMBL11413356 | 0.85 | PAOX (0.52) | ALDH1A1PAOXACHEFOLH1LMNA | |
| SCHEMBL24988252 | 0.85 | PAOX (0.52) | ALDH1A1PAOXACHEFOLH1LMNA | |
| SCHEMBL309977 | 0.78 | — | — | |
| SCHEMBL12719932 | 0.78 | PAOX (0.40) | ALDH1A1PAOXACHEFOLH1LMNA | |
| SCHEMBL14103859 | 0.78 | PAOX (0.40) | ALDH1A1PAOXACHEFOLH1LMNA | |
| SCHEMBL12719928 | 0.76 | PAOX (0.43) | ALDH1A1PAOXACHEFOLH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5775329-A | DERIVATIVES OF NOREPINEPHRINE USED TO STIMULATE EXERCISE STRESS AND ITS EFFECTS ON THE HEART. | GENSIA, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0833816-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040621-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1996-12-19 | — | — | WO | disclosed |