Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907132 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL29950661 | 0.81 | ERN1 (0.41) | DPP4TDP1POLBRECQLCASP6 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL29365114 | 0.78 | DPP4 (0.62) | DPP4ALDH1A1KDM4EHSD17B10TDP1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL117071 | 0.78 | DPP4 (0.62) | DPP4ALDH1A1KDM4EHSD17B10TDP1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL28092174 | 0.76 | DPP4 (0.60) | DPP4ALDH1A1KDM4EHSD17B10TDP1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL10490012 | 0.76 | DPP4 (0.60) | DPP4ALDH1A1KDM4EHSD17B10TDP1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL28055235 | 0.76 | DPP4 (0.60) | DPP4ALDH1A1KDM4EHSD17B10TDP1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL28587836 | 0.76 | DPP4 (0.50) | DPP4ALDH1A1KDM4EHSD17B10TDP1 | |
| SCHEMBL28395047 | 0.76 | ALDH1A1 (0.48) | DPP4ALDH1A1KDM4EHSD17B10TDP1 | |
| SCHEMBL486824 | 0.75 | DPP4 (0.71) | DPP4ALDH1A1KDM4EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |