Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | PLD2 | O14939 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562307 | 0.87 | KCNH2 (0.48) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| SCHEMBL9305692 | 0.86 | KCNH2 (0.45) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| SCHEMBL9304716 | 0.84 | KCNH2 (0.46) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| SCHEMBL9303798 | 0.84 | KCNH2 (0.47) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| SCHEMBL10508383 | 0.83 | HRH1 (0.80) | HRH1HRH4PLD2OPRM1OPRD1 | |
| Water SCHEMBL8560589 | 0.83 | OPRK1 (0.49) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| Water SCHEMBL9302653 | 0.82 | KCNH2 (0.43) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| SCHEMBL8560732 | 0.82 | KCNH2 (0.46) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| SCHEMBL9304456 | 0.81 | KCNH2 (0.51) | HRH1HRH4OPRM1OPRD1OPRK1 | |
| SCHEMBL14173615 | 0.79 | SSTR5 (0.51) | HRH1HRH4OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539421-B1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1998-09-23 | — | — | EP | disclosed |