Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564576 | 1.00 | HPGD (0.65) | HPGDHSD17B10EPHX2CYP1A2CYP3A4 | |
| SCHEMBL8562534 | 1.00 | HPGD (0.65) | HPGDHSD17B10EPHX2CYP1A2CYP3A4 | |
| SCHEMBL18593250 | 0.81 | HPGD (0.54) | HPGDHSD17B10EPHX2CYP1A2CYP3A4 | |
| SCHEMBL17432607 | 0.79 | HPGD (1.00) | HPGDHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8571139 | 0.79 | HPGD (0.76) | HPGDHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8571137 | 0.79 | HPGD (0.76) | HPGDHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4835296 | 0.78 | HPGD (0.79) | HPGDHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8568406 | 0.77 | HPGD (0.86) | HPGDHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8568399 | 0.77 | HPGD (0.86) | HPGDHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8568403 | 0.77 | HPGD (0.86) | HPGDHSD17B10CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |