Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568403 | 1.00 | HPGD (0.86) | HPGDKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL8568399 | 1.00 | HPGD (0.86) | HPGDKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL17432607 | 0.92 | HPGD (1.00) | HPGDKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL4835296 | 0.86 | HPGD (0.79) | HPGDKMT2AHSD17B10MEN1POLB | |
| SCHEMBL8571139 | 0.84 | HPGD (0.76) | HPGDKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL8571137 | 0.84 | HPGD (0.76) | HPGDKMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL8567989 | 0.80 | HPGD (0.69) | HPGDKMT2AHSD17B10MEN1SMN1; SMN2 | |
| SCHEMBL8567990 | 0.80 | HPGD (0.69) | HPGDKMT2AHSD17B10MEN1SMN1; SMN2 | |
| SCHEMBL8567992 | 0.80 | HPGD (0.69) | HPGDKMT2AHSD17B10MEN1SMN1; SMN2 | |
| SCHEMBL24377953 | 0.80 | HPGD (0.69) | HPGDKMT2AHSD17B10MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |