Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.40 |
| ▸ | F2 | P00734 | 13/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562636 | 1.00 | F10 (0.40) | F10F2PRSS1ACHE | |
| Hydrochloric Acid SCHEMBL8565347 | 0.99 | F10 (0.40) | F10F2PRSS1ACHE | |
| SCHEMBL8562349 | 0.94 | F2 (0.39) | F10F2ACHE | |
| SCHEMBL8562341 | 0.94 | F2 (0.39) | F10F2ACHE | |
| Hydrochloric Acid SCHEMBL8560749 | 0.93 | F2 (0.38) | F10F2PRSS1ACHE | |
| Hydrochloric Acid SCHEMBL8597445 | 0.92 | ACHE (0.37) | F10F2PRSS1ACHE | |
| Hydrochloric Acid SCHEMBL8566388 | 0.90 | F10 (0.36) | F10F2PRSS1ACHE | |
| SCHEMBL9413570 | 0.89 | ACHE (0.45) | F10F2PRSS1ACHE | |
| SCHEMBL9413572 | 0.89 | ACHE (0.45) | F10F2PRSS1ACHE | |
| Hydrochloric Acid SCHEMBL8559456 | 0.87 | DRD1 (0.37) | F10F2PRSS1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612741-B1 | Cyclic derivatives, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| EP-0612741-A1 | Cyclic derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-08-31 | — | — | EP | disclosed |