Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562698 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL7215935 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL7215932 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL23747401 | 0.83 | HRH3 (0.48) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| Hydrochloric Acid SCHEMBL7214381 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| Hydrochloric Acid SCHEMBL7214378 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL1542776 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL16874550 | 0.79 | KCNH2 (0.51) | LMNASMN1; SMN2 | |
| SCHEMBL8564966 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTT | |
| SCHEMBL8564961 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |