Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571410 | 1.00 | MMP2 (0.35) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8565588 | 0.86 | MMP2 (0.34) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8565202 | 0.86 | MMP2 (0.34) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8564128 | 0.83 | MMP2 (0.36) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8569517 | 0.83 | PTAFR (0.35) | PLAU | |
| SCHEMBL8570622 | 0.83 | PTAFR (0.35) | PLAU | |
| SCHEMBL8569363 | 0.81 | CA1 (0.39) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL8568591 | 0.72 | PTAFR (0.41) | PLAUALDH1A1 | |
| SCHEMBL8563029 | 0.72 | PTAFR (0.41) | PLAUALDH1A1 | |
| SCHEMBL8569673 | 0.72 | PTAFR (0.38) | MMP2MMP9MMP13PLAUALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | claimed |