⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556438 | 0.75 | — | — | |
| SCHEMBL8556441 | 0.75 | — | — | |
| SCHEMBL8019169 | 0.72 | — | — | |
| SCHEMBL29253718 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL7408676 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL4669593 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL2774228 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL2307604 | 0.69 | ALDH1A1 (0.48) | — | |
| SCHEMBL15962412 | 0.69 | ALDH1A1 (0.48) | — | |
| SCHEMBL3782478 | 0.69 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402854-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKENE ETHERS | NEUROBO PHARMACEUTICALS INC (US) | 2022-12-22 | — | — | US | disclosed |
| EP-3653598-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING , -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS | Gemphire Therapeutics Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20200048181-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS | NEUROBO PHARMACEUTICALS, INC. | 2020-02-13 | — | — | US | disclosed |
| US-10227285-B2 | Processes and intermediates for preparing alpha,omega-dicarboxylic acid-terminated dialkane ethers | GEMPHIRE THERAPEUTICS INC. (US) | 2019-03-12 | — | — | US | disclosed |
| US-20170158601-A9 | PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS | GEMPHIRE THERAPEUTICS INC. | 2017-06-08 | — | — | US | disclosed |
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| EP-0848015-A1 | Catalyst for the production of functionalized polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-17 | — | — | EP | disclosed |