Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 12/20 | 0.62 |
| ▸ | IKBKB | O14920 | 4/20 | 0.62 |
| ▸ | RARB | P10826 | 10/20 | 0.47 |
| ▸ | RARG | P13631 | 10/20 | 0.47 |
| ▸ | RXRA | P19793 | 9/20 | 0.45 |
| ▸ | RXRB | P28702 | 4/20 | 0.41 |
| ▸ | RXRG | P48443 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683402 | 0.86 | RARG (0.46) | RARAIKBKBRARBRARGRXRA | |
| SCHEMBL7683390 | 0.86 | RARG (0.46) | RARAIKBKBRARBRARGRXRA | |
| SCHEMBL7159498 | 0.86 | RARA (0.62) | RARAIKBKBRARBRARGRXRA | |
| SCHEMBL7685442 | 0.86 | RARA (0.62) | RARAIKBKBRARBRARGRXRA | |
| SCHEMBL7685449 | 0.86 | RARA (0.62) | RARAIKBKBRARBRARGRXRA | |
| SCHEMBL7159499 | 0.86 | RARA (0.62) | RARAIKBKBRARBRARGRXRA | |
| SCHEMBL7686286 | 0.85 | RARA (0.63) | RARAIKBKBRARBRARGHDAC11 | |
| SCHEMBL5888172 | 0.81 | RARA (0.77) | RARAIKBKBRARBRARG | |
| SCHEMBL5888298 | 0.81 | RARA (0.68) | RARAIKBKBRARBRARG | |
| SCHEMBL7686259 | 0.81 | RARG (0.50) | RARAIKBKBRARBRARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679628-B1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CIRD GALDERMA (FR) | 1998-04-22 | — | — | EP | disclosed |
| EP-0679628-A1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1995-11-02 | — | — | EP | disclosed |