Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981123 | 0.86 | TP53 (0.39) | TP53S1PR2S1PR1S1PR3CA2 | |
| SCHEMBL8968533 | 0.86 | DNM1 (0.42) | THRBCA2GGPS1 | |
| SCHEMBL8071713 | 0.86 | DNM1 (0.42) | THRBCA2GGPS1 | |
| SCHEMBL23001107 | 0.78 | TP53 (0.46) | TP53S1PR2S1PR1S1PR3CA2 | |
| SCHEMBL4703549 | 0.77 | TP53 (0.37) | TP53S1PR2S1PR1S1PR3CA2 | |
| Sulfuric Acid SCHEMBL27890973 | 0.76 | TP53 (0.50) | TP53S1PR2S1PR1S1PR3CA2 | |
| SCHEMBL26672072 | 0.76 | EPHX2 (0.46) | TP53EPHX2FAAH | |
| SCHEMBL9178018 | 0.76 | TP53 (0.39) | TP53THRBTHRACA2EPHX2 | |
| SCHEMBL23001173 | 0.74 | KDM5A (0.41) | S1PR2S1PR1S1PR3CA2EPHX2 | |
| SCHEMBL23927815 | 0.74 | KDM5A (0.41) | S1PR2S1PR1S1PR3CA2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763526-A | POLYURETHANES WITH ANIONIC AND CATIONIC GROUPS FOR COATING FILMS WITH ACID AND ALKALI RESISTANCE FOR DISPERSION STABILITY | NIPPON PAINT CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |