Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15148260 | 1.00 | F2 (0.48) | F2LTA4HMEN1KMT2ABCHE | |
| SCHEMBL7801902 | 0.87 | L3MBTL1 (0.54) | F2LTA4HMEN1KMT2ASIGMAR1 | |
| SCHEMBL15148092 | 0.87 | POLB (0.46) | LTA4HSIGMAR1 | |
| SCHEMBL23464746 | 0.86 | MEN1 (0.46) | MEN1KMT2ABCHEACHEMCHR1 | |
| SCHEMBL2706345 | 0.86 | MEN1 (0.46) | MEN1KMT2ABCHEACHEMCHR1 | |
| SCHEMBL203039 | 0.86 | MEN1 (0.46) | MEN1KMT2ABCHEACHEMCHR1 | |
| SCHEMBL2342290 | 0.86 | KMT2A (0.45) | F2LTA4HKMT2ABCHESIGMAR1 | |
| SCHEMBL16714074 | 0.85 | GRIN2D (0.56) | LTA4HSIGMAR1ALDH1A1 | |
| SCHEMBL3815944 | 0.85 | GRIN2D (0.56) | LTA4HSIGMAR1ALDH1A1 | |
| SCHEMBL3815948 | 0.85 | GRIN2D (0.56) | LTA4HSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849746-A | Substituted 1,4-piperazine-heteroaryl derivatives as 5-HT1D receptor agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-12-15 | — | — | US | disclosed |