Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17799397 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BEPHX2TOP2AIDO1 | |
| SCHEMBL8563182 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BEPHX2TOP2AIDO1 | |
| SCHEMBL7424505 | 0.83 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2IDO1MEN1 | |
| SCHEMBL7418105 | 0.78 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2IDO1MEN1 | |
| SCHEMBL7418106 | 0.78 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2IDO1MEN1 | |
| SCHEMBL8561678 | 0.78 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2IDO1MEN1 | |
| SCHEMBL22283168 | 0.78 | TOP2A (0.37) | MTNR1AEPHX2TOP2ADUTEHMT2 | |
| SCHEMBL18576830 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2IDO1MEN1 | |
| SCHEMBL17785846 | 0.76 | EPHX2 (0.45) | MTNR1AMTNR1BEPHX2IDO1MEN1 | |
| SCHEMBL16096739 | 0.74 | SYK (0.39) | TOP2ADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |