SCHEMBL8563196

SCHEMBL8563196

CCCCCCc1cccc(CCCCCC)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.67
LIPG Q9Y5X9 3/20 0.67
PPARG P37231 1/20 0.56
PPARA Q07869 1/20 0.56
ESR1 P03372 2/20 0.54
ADRA2A P08913 2/20 0.54
ADORA3 P0DMS8 2/20 0.54
TACR2 P21452 2/20 0.54
SLC6A2 P23975 2/20 0.54
SLC6A4 P31645 2/20 0.54
SLC6A3 Q01959 2/20 0.54
PTGS2 P35354 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
SHBG P04278 1/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
HSPD1 P10809 1/20 0.54
ADRB3 P13945 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29742685 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL4211261 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL11746219 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL10518886 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL5249436 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL6932623 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL4032533 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL27683349 1.00 LPL (0.67) LPLLIPGPPARGPPARAESR1
SCHEMBL2461697 0.98 LPL (0.65) LPLLIPGPPARGPPARAESR1
SCHEMBL11577802 0.98 LPL (0.65) LPLLIPGPPARGPPARAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103619987-B Color converter 巴斯夫欧洲公司 2016-11-16 CN disclosed
CN-103270111-B Composition and block copolymer 住友化学株式会社 2016-07-20 CN disclosed
US-5756730-A Process for preparing analgesic compounds SANKYO COMPANY, LIMITED (JP) 1998-05-26 US disclosed
CN-1036004-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1997-10-01 CN disclosed
US-5656758-A AMIDATION OF AN AMINE-CONTAINING THIOMORPHOLINE OR PIPERAZINE COMPOUND SANKYO COMPANY, LIMITED (JP) 1997-08-12 US disclosed
CN-1034731-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1997-04-30 CN disclosed
US-5512567-A KAPPA-RECEPTOR AGONISTS SANKYO COMPANY, LIMITED (JP) 1996-04-30 US disclosed
CN-1030450-C Preparation of analgesic carboxylic acid amides derivative SANKYO CO (JP) 1995-12-06 CN disclosed
CN-1079740-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-12-22 CN disclosed
CN-1079741-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-12-22 CN disclosed
US-5270327-A Piperidine derivatives SANKYO COMPANY, LIMITED (JP) 1993-12-14 US disclosed
CN-1078461-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-11-17 CN disclosed
CN-1022185-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-09-22 CN disclosed
EP-0356247-B1 ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES Sankyo Company Limited (JP) 1993-03-17 EP disclosed
US-5021413-A Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them SANKYO COMPANY LIMITED (JP) 1991-06-04 US disclosed
CN-1040791-A ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES SANKYO CO (JP) 1990-03-28 CN disclosed
EP-0356247-A1 Analgesic carboxylic acid amide derivatives Sankyo Company Limited (JP) 1990-02-28 EP disclosed
US-4039793-A PRODUCTION OF MONOCHLORO- AND ARYL SUBSTITUTED SATURATED COMPOUNDS UOP INC. (US) 1977-08-02 US disclosed