Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635020 | 0.88 | ACAT1 (0.51) | ACAT1SOAT1LPAR1 | |
| SCHEMBL6634842 | 0.86 | ACAT1 (0.48) | ACAT1SOAT1LPAR1 | |
| SCHEMBL6635500 | 0.85 | ACAT1 (0.53) | ACAT1SOAT1LPAR1 | |
| SCHEMBL8566791 | 0.85 | ACAT1 (0.49) | ACAT1SOAT1 | |
| SCHEMBL6638335 | 0.85 | ACAT1 (0.53) | ACAT1SOAT1LPAR1 | |
| SCHEMBL8566199 | 0.85 | ACAT1 (0.45) | ACAT1SOAT1ELANELPAR1 | |
| SCHEMBL8566661 | 0.84 | ACAT1 (0.46) | ACAT1SOAT1LPAR1 | |
| SCHEMBL8566579 | 0.84 | ACAT1 (0.45) | ACAT1SOAT1LPAR1 | |
| SCHEMBL6637488 | 0.83 | ACAT1 (0.49) | ACAT1SOAT1LPAR1 | |
| SCHEMBL6637035 | 0.83 | ACAT1 (0.57) | ACAT1SOAT1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842933-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |