Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562506 | 0.90 | PKM (0.48) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8570365 | 0.89 | PKM (0.47) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3577502 | 0.88 | PKM (0.53) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29543480 | 0.83 | TAAR1 (0.56) | PKM | |
| SCHEMBL14655775 | 0.83 | TAAR1 (0.56) | PKM | |
| SCHEMBL9971029 | 0.81 | PKM (0.53) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8561757 | 0.81 | PKM (0.45) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8563990 | 0.80 | SSTR5 (0.47) | PKMKDM4EALDH1A1SSTR5SLC2A1 | |
| SCHEMBL22778208 | 0.79 | PKM (0.49) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| Bromide SCHEMBL22778255 | 0.79 | PKM (0.49) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549366-B1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-04-15 | — | — | EP | disclosed |
| CN-1033639-C | Benzoquinonyl-containing thiazolidine compound, preparing process thereof and its application in medicine | SANKYO CO (JP) | 1996-12-25 | — | — | CN | disclosed |
| CN-1032751-C | thiazolidine compounds, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-09-11 | — | — | CN | disclosed |
| EP-0549365-B1 | Thiazolidine compounds, their preparation and their therapeutic uses | SANKYO CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5338855-A | Treating diabetes or hyperlipemia | SANKYO COMPANY, LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| CN-1074679-A | Its preparation of thiazolidine compound and the therepic use thereof that contain quinonyl | SANKYO CO (JP) | 1993-07-28 | — | — | CN | disclosed |
| CN-1074680-A | Thiazolidine compound, its preparation and therepic use thereof | SANKYO CO (JP) | 1993-07-28 | — | — | CN | disclosed |
| EP-0549366-A1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0549365-A1 | Thiazolidine compounds, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |