Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8563740 | 0.99 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9390843 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8569136 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8563064 | 0.84 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8875209 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2 | |
| Ethyl Acetate SCHEMBL9390022 | 0.80 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8561087 | 0.77 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL8873699 | 0.75 | PPARG (0.54) | AGTR1AGTR2 | |
| SCHEMBL8872752 | 0.74 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8563050 | 0.73 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649424-B1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | KNOLL AG (DE) | 1998-10-07 | — | — | EP | claimed |
| WO-1994001436-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1994-01-20 | — | — | WO | claimed |
| EP-0649424-B1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | KNOLL AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5627191-A | Therapeutic agents | THE BOOTS COMPANY PLC (GB) | 1997-05-06 | — | — | US | disclosed |
| EP-0649424-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | Knoll AG (DE) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001436-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1994-01-20 | — | — | WO | disclosed |