SCHEMBL8563368

SCHEMBL8563368

COC1C=CC=CC1(OC)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19321593 0.85
SCHEMBL28350465 0.80 TSHR (0.37)
SCHEMBL8413587 0.78
SCHEMBL3805574 0.76
SCHEMBL16245214 0.73
SCHEMBL2551319 0.72
SCHEMBL5170532 0.72 POLB (0.35)
SCHEMBL9591208 0.70 TDP1 (0.33)
SCHEMBL28442226 0.70 NPC1 (0.40)
SCHEMBL20527383 0.69 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024170002-A1 NOVEL EPISULFIDE COMPOUND AND OPTICAL MATERIAL COMPOSITION THEREOF 益丰新材料股份有限公司 2024-08-22 WO disclosed
CN-106938997-B N- (4- replaces phenethyl) acetamides and application thereof 华东理工大学 2019-10-11 CN disclosed
CN-106938997-A N (4 substitution phenethyl) acetamides and application thereof 华东理工大学 2017-07-11 CN disclosed
US-9631159-B2 Lubricating composition containing a salt of a carboxylic acid THE LUBRIZOL CORPORATION (US) 2017-04-25 US disclosed
US-20160097018-A1 LUBRICATING COMPOSITION CONTAINING A SALT OF A CARBOXYLIC ACID LUBRIZOL CORP (US) 2016-04-07 US disclosed
US-9243202-B2 Lubricating composition containing a salt of a carboxylic acid THE LUBRIZOL CORPORATION (US) 2016-01-26 US disclosed
US-20150141307-A1 Lubricating Composition Containing a Salt of a Carboxylic Acid THE LUBRIZOL CORPORATION (US) 2015-05-21 US disclosed
EP-0863881-A1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-09-16 EP disclosed
WO-1997010219-A1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-03-20 WO disclosed