Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etalocib SCHEMBL29379752 | 0.89 | LTB4R (1.00) | LTB4RLTB4R2 | |
| Etalocib SCHEMBL1649516 | 0.89 | LTB4R (1.00) | LTB4RLTB4R2 | |
| Etalocib SCHEMBL6356831 | 0.88 | LTB4R (0.98) | LTB4RLTB4R2 | |
| Etalocib SCHEMBL4306319 | 0.88 | LTB4R (0.98) | LTB4RLTB4R2 | |
| SCHEMBL6898153 | 0.87 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL13696754 | 0.87 | LTB4R (0.86) | LTB4RLTB4R2 | |
| SCHEMBL6899046 | 0.86 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL7624513 | 0.86 | LTB4R (0.84) | LTB4RLTB4R2 | |
| Etalocib SCHEMBL4306317 | 0.85 | LTB4R (0.83) | LTB4RLTB4R2 | |
| SCHEMBL6897565 | 0.85 | LTB4R (1.00) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| WO-1996036347-A1 | USE OF LEUKOTRIENE ANTAGONISTS FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1996-11-21 | — | — | WO | disclosed |
| EP-0743064-A1 | Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease | ELI LILLY AND COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5462954-A | Antiinflammatory, antiallergens; treating asthma | ELI LILLY AND COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |