Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8563404 | 1.00 | ALDH1A1 (0.49) | ALDH1A1ANPEPLMNAKCNJ1USP2 | |
| SCHEMBL8558131 | 0.84 | USP2 (0.47) | ALDH1A1ANPEPLMNAUSP2NPC1 | |
| SCHEMBL8558133 | 0.84 | USP2 (0.47) | ALDH1A1ANPEPLMNAUSP2NPC1 | |
| Trifluoroacetic Acid SCHEMBL27638155 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ANPEPLMNAKCNJ1USP2 | |
| SCHEMBL9546912 | 0.72 | ALDH1A1 (0.40) | ALDH1A1ANPEPLMNAUSP2NPC1 | |
| Trifluoroacetic Acid SCHEMBL6229501 | 0.71 | SLC7A5 (0.43) | ANPEPLMNADPP4DPP8SLC7A5 | |
| Trifluoroacetic Acid SCHEMBL27041458 | 0.71 | GAA (0.47) | ALDH1A1LMNAKCNJ1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL3750649 | 0.70 | KDM4E (0.75) | ALDH1A1LMNAKCNJ1USP2KDM4E | |
| Trifluoroacetic Acid SCHEMBL3750654 | 0.70 | SMN1; SMN2 (0.50) | ALDH1A1LMNAKCNJ1KDM4EHSD17B10 | |
| SCHEMBL372508 | 0.70 | USP2 (0.58) | ALDH1A1ANPEPLMNAUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543861-B1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIOTECH PHARM (GB) | 1998-10-14 | — | — | EP | disclosed |
| US-5276153-A | Antagonist of platelet activating factor for bronchodilation | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-01-04 | — | — | US | disclosed |
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |