Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30536641 | 0.88 | CTSK (0.47) | CTSKALDH1A1CA1CA2CA7 | |
| SCHEMBL1414331 | 0.84 | CTSK (0.43) | CTSKALDH1A1CA1CA2CA7 | |
| SCHEMBL17828217 | 0.84 | CTSK (0.43) | CTSKALDH1A1CTSLCTSBCD274 | |
| SCHEMBL1414330 | 0.84 | CTSK (0.43) | CTSKALDH1A1CA1CA2CA7 | |
| SCHEMBL13994293 | 0.84 | CHRM5 (0.41) | CTSKCA1CA2CA7CTSL | |
| SCHEMBL12260408 | 0.83 | CTSK (0.49) | CTSKALDH1A1CA1CA2CA7 | |
| SCHEMBL2255069 | 0.83 | CTSK (0.49) | CTSKALDH1A1CA1CA2CA7 | |
| SCHEMBL357027 | 0.83 | CTSK (0.49) | CTSKALDH1A1CA1CA2CA7 | |
| SCHEMBL8234411 | 0.81 | CTSK (0.44) | CTSKALDH1A1CA2CTSLCTSB | |
| SCHEMBL13994318 | 0.80 | HRH2 (0.40) | CTSKALDH1A1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543861-B1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIOTECH PHARM (GB) | 1998-10-14 | — | — | EP | disclosed |
| US-5276153-A | Antagonist of platelet activating factor for bronchodilation | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-01-04 | — | — | US | disclosed |
| EP-0543861-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |