SCHEMBL8563548

SCHEMBL8563548

CCOC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1cc(Cl)cc(OC)n1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.40
POLB P06746 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 2/20 0.39
P2RY12 Q9H244 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorimuron Ethyl SCHEMBL54938 0.85 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTTDP1
Chlorimuron Ethyl SCHEMBL9141286 0.85 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTTDP1
Chlorimuron Ethyl SCHEMBL29370868 0.85 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTTDP1
Chlorimuron Ethyl SCHEMBL20214247 0.85 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTTDP1
Chlorimuron Ethyl SCHEMBL15524976 0.85 ALDH1A1 (0.47) ALDH1A1KDM4ENPC1MAPTTDP1
Chlorimuron Ethyl SCHEMBL20723617 0.85 ALDH1A1 (0.47) ALDH1A1KDM4ENPC1MAPTTDP1
Chlorimuron Ethyl SCHEMBL9422513 0.82 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTTDP1
SCHEMBL27614193 0.80 MEN1 (0.48) ALDH1A1KDM4ENPC1MAPTTSHR
SCHEMBL1535824 0.79 SMN1; SMN2 (0.43) ALDH1A1KDM4ENPC1MAPTTDP1
Chlorimuron Ethyl SCHEMBL3807747 0.78 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548593-B1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient MITSUBISHI CHEM CORP (JP) 1998-04-22 EP disclosed
US-5405828-A Selective pre- and postemergence herbicides MITSUBISHI KASEI CORPORATION (JP) 1995-04-11 US disclosed
US-5324709-A Safety on crops MITSUBISHI KASEI CORPORATION (JP) 1994-06-28 US disclosed
EP-0294666-B1 Substituted triazolinones BAYER AG (DE) 1994-02-16 EP disclosed
EP-0548593-A1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient Mitsubishi Chemical Corporation (JP) 1993-06-30 EP disclosed
US-4874424-A ALKOXIMINOALKYLAMIDE BAYER AKTIENGESELLSCHAFT (DE) 1989-10-17 US disclosed
EP-0289927-A2 Herbicidal agents BAYER AG (DE) 1988-11-09 EP disclosed