Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813401 | 0.94 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| Sulfuric Acid SCHEMBL7749074 | 0.88 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| Sulfuric Acid SCHEMBL11044859 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| Oxirane SCHEMBL11593723 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| Methanesulfonamide SCHEMBL9569316 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| SCHEMBL11025440 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| Methanesulfonamide SCHEMBL11294048 | 0.83 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| SCHEMBL6342530 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| SCHEMBL9515690 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TDP1RECQLTHRB | |
| SCHEMBL10709767 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TDP1RECQLTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773205-A | Film spool cartridge and camera containing duplitized color silver halide photographic element | EASTMAN KODAK COMPANY (US) | 1998-06-30 | — | — | US | disclosed |