Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARG | P13631 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559500 | 0.76 | RARA (0.33) | RARARARBRARG | |
| SCHEMBL6088929 | 0.76 | KDM4E (0.36) | RARARARBRARG | |
| SCHEMBL8565764 | 0.73 | RARA (0.39) | RARARARBRARG | |
| SCHEMBL6595814 | 0.72 | RARA (0.38) | RARARARBRARG | |
| SCHEMBL6087866 | 0.70 | PDE4B (0.36) | RARARARBRARG | |
| SCHEMBL6086714 | 0.70 | PDK2 (0.34) | RARARARBRARG | |
| SCHEMBL6552888 | 0.70 | RARA (0.34) | RARARARBRARG | |
| SCHEMBL7597729 | 0.69 | RARA (0.32) | RARARARBRARG | |
| SCHEMBL6292648 | 0.69 | RARA (0.43) | RARARARBRARG | |
| SCHEMBL6297202 | 0.69 | RARB (0.51) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808124-A | BINDING TO RETINOID RECEPTORS | ALLERGAN (US) | 1998-09-15 | — | — | US | disclosed |
| US-5773594-A | TREATING SKIN DISORDERS, REDUCING SIDE EFFECTS OF OTHER RETINOIDS | ALLERGAN (US) | 1998-06-30 | — | — | US | disclosed |
| US-5763635-A | Tetrahydronaphthalene derivatives substituted in the 8 position with alkyhidene groups having retinoid and/or retinoid antagonist-like biological activity | ALLERGAN (US) | 1998-06-09 | — | — | US | disclosed |
| US-5747542-A | SKIN DISORDERS; ANTICANCER AGENTS | ALLERGAN (US) | 1998-05-05 | — | — | US | disclosed |
| US-5741896-A | O- or S- substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity | ALLERGAN (US) | 1998-04-21 | — | — | US | disclosed |