Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563940 | 1.00 | PPARG (0.46) | PPARGPPARASLC1A5GRIK1GRIK2 | |
| SCHEMBL8562536 | 0.81 | SLC1A1 (0.47) | PPARGPPARAGRIK1SLC1A1SLC1A3 | |
| SCHEMBL8562527 | 0.81 | SLC1A1 (0.47) | PPARGPPARAGRIK1SLC1A1SLC1A3 | |
| SCHEMBL3879629 | 0.81 | SMN1; SMN2 (0.57) | PPARGPPARA | |
| SCHEMBL8935641 | 0.81 | SMN1; SMN2 (0.57) | PPARGPPARA | |
| SCHEMBL8564033 | 0.79 | GRIK1 (0.48) | PPARGPPARAGRIK1GRIK2SLC1A1 | |
| SCHEMBL8564030 | 0.79 | GRIK1 (0.48) | PPARGPPARAGRIK1GRIK2SLC1A1 | |
| SCHEMBL8559217 | 0.79 | PPARG (0.53) | PPARGPPARASLC1A1SLC1A3SLC1A2 | |
| SCHEMBL8559220 | 0.79 | PPARG (0.53) | PPARGPPARASLC1A1SLC1A3SLC1A2 | |
| SCHEMBL27731608 | 0.78 | ATM (0.49) | PPARGSLC1A5GRIK1GRIK2GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |