Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567729 | 1.00 | KMT2A (0.51) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL29347468 | 0.82 | KMT2A (0.47) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL9725029 | 0.81 | KMT2A (0.58) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL4169644 | 0.81 | KMT2A (0.58) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL13595511 | 0.81 | KMT2A (0.58) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL93708 | 0.80 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL4382418 | 0.80 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL93709 | 0.80 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL4385964 | 0.80 | CA1 (0.66) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL4135904 | 0.80 | CA1 (0.46) | KMT2ACA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837868-A | REACTION OF DIHYDROXY OLEFINS IN A MULTISTAGE PROCESS ARYL METHYLAMINE TO FORM PYRROLIDINE INTERMEDIATE | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1998022437-A1 | PROCESS FOR PREPARATION OF CHIRAL 3-AMINOPYRROLIDINE AND ANALOGOUS BICYCLIC COMPOUNDS | ABBOTT LABORATORIES (US) | 1998-05-28 | — | — | WO | disclosed |
| US-5703244-A | CYCLIZATION OF DIHYDROXY OLEFINS WITH TARTRATE ESTER IN PRESENCE OF TITANIUM ISOPROPOXIDE AND TERT-BUTYL HYDROPEROXIDE | ABBOTT LABORATORIES (US) | 1997-12-30 | — | — | US | disclosed |