Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15498497 | 1.00 | CA1 (0.46) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL4768128 | 1.00 | CA1 (0.46) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL24215046 | 0.91 | CA1 (0.49) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL29347468 | 0.87 | KMT2A (0.47) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL8193335 | 0.87 | TDP1 (0.37) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL31208336 | 0.84 | CA1 (0.51) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL8560881 | 0.81 | TDP1 (0.37) | CA1KMT2ATDP1TSHR | |
| SCHEMBL8566056 | 0.81 | TDP1 (0.37) | CA1KMT2ATDP1TSHR | |
| SCHEMBL4129150 | 0.80 | ALDH1A1 (0.51) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL4129154 | 0.80 | ALDH1A1 (0.51) | CA1CA2CA7CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | TRPV4, TRPC4, TRPV1 | CA1 1033/4885CA2 182/4885CA7 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.