Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 1/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.60 |
| ▸ | PLAT | P00750 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25350049 | 0.96 | MAPT (0.61) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL6565993 | 0.91 | KMT2A (0.68) | KMT2AMAPTMEN1NPC1PKM | |
| 4-Nitrobenzoyl Chloride SCHEMBL8699157 | 0.91 | F10 (0.58) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL25349969 | 0.88 | MAPT (0.60) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL25350302 | 0.88 | KMT2A (0.58) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL4263585 | 0.88 | P2RX1 (0.64) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL25347296 | 0.85 | P2RX1 (0.60) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL25347834 | 0.85 | MAPT (0.56) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL25350206 | 0.85 | MAPT (0.63) | KMT2AMAPTMEN1NPC1PKM | |
| SCHEMBL25347962 | 0.85 | MAPT (0.56) | KMT2AMAPTMEN1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237547-B | A kind of preparation method of hydroxyl benzoxazole | 中国科学院长春应用化学研究所 | 2017-11-14 | — | — | CN | disclosed |
| WO-1998024776-A1 | PREPARATION OF AN AMINOARYLAMINOARAZOLE | THE DOW CHEMICAL COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| US-5739344-A | Preparation of an aminoarylaminoarazole | THE DOW CHEMICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |