Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
| ▸ | PLAT | P00750 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564166 | 0.91 | KMT2A (0.61) | F10PLAUPLATALDH1A1MAPT | |
| SCHEMBL25350049 | 0.87 | MAPT (0.61) | F10PLAUPLATALDH1A1MAPT | |
| SCHEMBL7879019 | 0.83 | KMT2A (0.71) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL4263585 | 0.83 | P2RX1 (0.64) | F10PLAUPLATALDH1A1MAPT | |
| SCHEMBL6565993 | 0.82 | KMT2A (0.68) | ALDH1A1MAPTKMT2APOLBMEN1 | |
| SCHEMBL25353807 | 0.81 | KMT2A (0.60) | F10PLAUPLATALDH1A1MAPT | |
| SCHEMBL25350302 | 0.80 | KMT2A (0.58) | F10PLAUPLATALDH1A1MAPT | |
| SCHEMBL25349969 | 0.80 | MAPT (0.60) | F10PLAUPLATALDH1A1MAPT | |
| SCHEMBL25347296 | 0.80 | P2RX1 (0.60) | F10PLAUPLATALDH1A1MAPT | |
| SCHEMBL28044831 | 0.78 | MAPT (0.84) | ALDH1A1MAPTKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998024776-A1 | PREPARATION OF AN AMINOARYLAMINOARAZOLE | THE DOW CHEMICAL COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |