Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 12/20 | 0.44 |
| ▸ | PPARG | P37231 | 11/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564253 | 1.00 | GRIK1 (0.49) | GRIK1GRIK2PPARAPPARGKIF11 | |
| SCHEMBL8558724 | 0.84 | PPARG (0.55) | GRIK1GRIK2PPARAPPARGKIF11 | |
| SCHEMBL8560351 | 0.84 | PPARG (0.59) | GRIK1GRIK2PPARAPPARGKIF11 | |
| SCHEMBL8558721 | 0.84 | PPARG (0.55) | GRIK1GRIK2PPARAPPARGKIF11 | |
| SCHEMBL8559317 | 0.84 | PPARG (0.55) | GRIK1GRIK2PPARAPPARGKIF11 | |
| SCHEMBL8559217 | 0.82 | PPARG (0.53) | PPARAPPARG | |
| SCHEMBL8559220 | 0.82 | PPARG (0.53) | PPARAPPARG | |
| SCHEMBL8935922 | 0.81 | SMN1; SMN2 (0.61) | PPARAPPARGSMN1; SMN2RXRARXRB | |
| SCHEMBL4030805 | 0.81 | SMN1; SMN2 (0.61) | PPARAPPARGSMN1; SMN2RXRARXRB | |
| SCHEMBL8564512 | 0.80 | PPARG (0.63) | GRIK1GRIK2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |