Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 17/20 | 0.52 |
| ▸ | PPARG | P37231 | 16/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030805 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2PPARAPPARGRXRARXRB | |
| SCHEMBL3028298 | 0.84 | PPARA (0.68) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935879 | 0.84 | PPARA (0.68) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL442891 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL1565487 | 0.84 | PPARA (0.55) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL11550284 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL21991991 | 0.82 | PPARG (0.66) | SMN1; SMN2PPARAPPARGTSHR | |
| SCHEMBL8935844 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL433427 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935859 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |