Sugi Predict

Sugi Predict / Compounds / SCHEMBL8564293

SCHEMBL8564293

SCHEMBL8564293

CC(=O)N(C)c1c(Cl)cc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BDKRB2 P30411 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8569986 0.99 BDKRB2 (0.67) BDKRB2
SCHEMBL8565902 0.92 BDKRB2 (0.61) BDKRB2
SCHEMBL8569550 0.88 BDKRB2 (0.62) BDKRB2
Hydrochloric Acid SCHEMBL8565632 0.87 BDKRB2 (0.63) BDKRB2
SCHEMBL8560851 0.86 BDKRB2 (0.81) BDKRB2
Hydrochloric Acid SCHEMBL8566083 0.85 BDKRB2 (0.81) BDKRB2
SCHEMBL8563138 0.85 BDKRB2 (0.66) BDKRB2
SCHEMBL8567795 0.84 BDKRB2 (0.79) BDKRB2
SCHEMBL8567070 0.81 BDKRB2 (0.59) BDKRB2
SCHEMBL8672788 0.81 BDKRB2 (0.45) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596406-B1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO (JP) 1998-12-16 — — EP disclosed
US-5574042-A ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN FUJISAWA PHARMACEUTICAL CO., LTD (JP) 1996-11-12 — — US disclosed
EP-0596406-A1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-05-11 — — EP disclosed