SCHEMBL8564373

SCHEMBL8564373

Cc1ccc(OS(=O)(=O)c2ccccc2)cn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.53
MAOB P27338 2/20 0.46
MAPT P10636 4/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
METAP2 P50579 1/20 0.44
METAP1 P53582 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
ALPL P05186 2/20 0.42
ALPI P09923 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HSP90AA1 P07900 1/20 0.42
XBP1 P17861 1/20 0.42
MPI P34949 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10684102 0.87 MEN1 (0.49) MAPTL3MBTL1GAAHTTALDH1A1
SCHEMBL6814536 0.78 TDP1 (0.50) TDP1MAOBMAPTNPC1RAB9A
SCHEMBL27702182 0.77 TDP1 (0.46) TDP1MAOBMAPTNPC1RAB9A
SCHEMBL564671 0.77 TDP1 (0.46) TDP1MAOBMAPTNPC1RAB9A
SCHEMBL2237142 0.77 TDP1 (0.67) TDP1MAOBMAPTNPC1RAB9A
SCHEMBL8559907 0.76 TDP1 (0.49) TDP1MAOBMAPTNPC1RAB9A
SCHEMBL564269 0.76 TDP1 (0.49) TDP1MAOBMAPTNPC1RAB9A
SCHEMBL11294092 0.76 TDP1 (0.51) TDP1MAOBMAPTMETAP2METAP1
SCHEMBL752015 0.76 CXCR2 (0.39) MAPTCA2
SCHEMBL27667393 0.75 MAOB (0.48) TDP1MAOBMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5760237-A Synthesis of l-azatyrosine using pseudoephedrine as a chiral auxiliary CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-06-02 US disclosed