Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255332 | 0.85 | KMT2A (0.45) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL8564373 | 0.78 | TDP1 (0.53) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL31428799 | 0.77 | TUBB4A (0.36) | ALDH1A1MAPTHPGDHTTKDM4E | |
| SCHEMBL510017 | 0.75 | LTA4H (0.44) | ALDH1A1SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL8559907 | 0.74 | TDP1 (0.49) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL564269 | 0.74 | TDP1 (0.49) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL27702182 | 0.72 | TDP1 (0.46) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL27702178 | 0.72 | TDP1 (0.46) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL564671 | 0.72 | TDP1 (0.46) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL19146 | 0.71 | TDP1 (0.73) | TDP1ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012656-A2 | THIOPHENE AND FURAN DERIVATIVES AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-02-12 | — | — | WO | disclosed |