Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | BLM | P54132 | 4/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562107 | 0.96 | HSD17B10 (0.40) | HSD17B10CYP1A2HIF1ABCHEACHE | |
| SCHEMBL8596326 | 0.85 | BCHE (0.36) | HSD17B10CYP1A2HIF1ABCHEACHE | |
| SCHEMBL8557371 | 0.83 | ADRB2 (0.45) | HSD17B10CYP1A2HIF1ABCHEACHE | |
| SCHEMBL8651693 | 0.81 | BCHE (0.37) | HSD17B10CYP1A2HIF1ABCHEACHE | |
| SCHEMBL8559579 | 0.81 | ADRB2 (0.39) | HSD17B10CYP1A2HIF1ABCHEACHE | |
| SCHEMBL8560539 | 0.80 | ADRB2 (0.58) | HSD17B10CYP1A2HIF1AADRB2TDP1 | |
| SCHEMBL8560544 | 0.80 | ADRB2 (0.58) | HSD17B10CYP1A2HIF1AADRB2TDP1 | |
| Oxalic Acid SCHEMBL8562340 | 0.80 | ADRB2 (0.52) | HSD17B10CYP1A2HIF1AADRB2TDP1 | |
| Oxalic Acid SCHEMBL8560131 | 0.80 | ADRB2 (0.52) | HSD17B10CYP1A2HIF1AADRB2TDP1 | |
| SCHEMBL8563319 | 0.76 | ADRB2 (0.56) | HSD17B10CYP1A2HIF1AADRB2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5775329-A | DERIVATIVES OF NOREPINEPHRINE USED TO STIMULATE EXERCISE STRESS AND ITS EFFECTS ON THE HEART. | GENSIA, INC. (US) | 1998-07-07 | — | — | US | disclosed |