Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.38 |
| ▸ | ADH1A | P07327 | 4/20 | 0.38 |
| ▸ | ADH7 | P40394 | 3/20 | 0.38 |
| ▸ | ADH1C | P00326 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543731 | 0.77 | TSHR (0.39) | TSHRTRPV1TDP1CHRM2CHRM4 | |
| SCHEMBL10782810 | 0.75 | TSHR (0.50) | TSHRTRPV1TDP1CHRM2CHRM4 | |
| SCHEMBL8726324 | 0.74 | ADH1B (0.44) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL27449129 | 0.73 | HIF1A (0.36) | TSHRTRPV1TDP1CHRM2CHRM4 | |
| SCHEMBL16305427 | 0.72 | ADH1B (0.42) | ADH1BADH1AADH1CTSHRTRPV1 | |
| SCHEMBL16305419 | 0.72 | ADH1B (0.38) | ADH1BADH1AADH7ADH1CTSHR | |
| SCHEMBL2230506 | 0.71 | TSHR (0.46) | TSHRTRPV1TDP1CHRM2CHRM4 | |
| SCHEMBL8289079 | 0.69 | ADH1B (0.43) | ADH1BADH1AADH7ADH1CTSHR | |
| SCHEMBL16381892 | 0.69 | ADH1B (0.35) | ADH1BADH1AADH7ADH1C | |
| SCHEMBL16305403 | 0.69 | ADH1B (0.35) | ADH1BADH1AADH7ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |