Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564547 | 1.00 | CTSK (0.39) | CTSKCTSSCTSLCTSBPSEN1 | |
| SCHEMBL8570019 | 0.82 | CTSK (0.48) | CTSKCA1CA2CA7 | |
| SCHEMBL8563614 | 0.82 | CTSK (0.48) | CTSKCA1CA2CA7 | |
| SCHEMBL8563616 | 0.82 | CTSK (0.48) | CTSKCA1CA2CA7 | |
| SCHEMBL30441268 | 0.81 | CTSK (0.44) | CTSKCTSSCTSLCTSBPSEN1 | |
| SCHEMBL18082620 | 0.80 | CTSK (0.43) | CTSKCTSSCTSLCTSBPSEN1 | |
| SCHEMBL25008491 | 0.80 | CTSK (0.49) | CTSKCTSSCTSLCTSBPSENEN | |
| SCHEMBL18082613 | 0.79 | CTSK (0.42) | CTSKCTSSCTSLCTSBPSEN1 | |
| SCHEMBL3935052 | 0.78 | SMN1; SMN2 (0.44) | CTSKCTSSCTSLCTSBPSEN1 | |
| SCHEMBL3194820 | 0.77 | CTSK (0.43) | CTSKCTSSCTSLCTSBPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |