Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | PREP | P48147 | 3/20 | 0.46 |
| ▸ | FAP | Q12884 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564779 | 1.00 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29985759 | 0.97 | PREP (0.44) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29349875 | 0.96 | DPP4 (0.43) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29595774 | 0.94 | CHRM3 (0.43) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29935652 | 0.92 | CHRM3 (0.42) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29380104 | 0.88 | ACE (0.49) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29874508 | 0.88 | ACE (0.49) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL1046072 | 0.88 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL1046070 | 0.88 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL1402279 | 0.88 | CHRM2 (0.42) | DPP4PREPFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545991-B1 | PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF | VAHLNE ANDERS (SE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0545991-B1 | PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF | VAHLNE ANDERS (SE) | 1998-12-02 | — | — | EP | disclosed |
| US-5627035-A | Peptides that block human immunodeficiency virus and methods of use thereof | SYNTELLO VACCINE DEVELOPMENT AB (SE) | 1997-05-06 | — | — | US | disclosed |
| EP-0545991-A1 | PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF | VAHLNE, Anders (SE) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992003147-A1 | PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF | SYNTELLO VACCIN DEVELOPMENT KB (SE) | 1992-03-05 | — | — | WO | disclosed |