SCHEMBL8564779

SCHEMBL8564779

NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.46
PREP P48147 3/20 0.46
FAP Q12884 3/20 0.46
DPP8 Q6V1X1 2/20 0.46
DPP9 Q86TI2 1/20 0.46
ACE P12821 3/20 0.41
F2 P00734 4/20 0.40
PRSS1 P07477 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 1/20 0.39
DPP7 Q9UHL4 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8564777 1.00 DPP4 (0.46) DPP4PREPFAPDPP8DPP9
SCHEMBL29985759 0.97 PREP (0.44) DPP4PREPFAPDPP8DPP9
SCHEMBL29349875 0.96 DPP4 (0.43) DPP4PREPFAPDPP8DPP9
SCHEMBL29595774 0.94 CHRM3 (0.43) DPP4PREPFAPDPP8DPP9
SCHEMBL29935652 0.92 CHRM3 (0.42) DPP4PREPFAPDPP8DPP9
SCHEMBL29380104 0.88 ACE (0.49) DPP4PREPFAPDPP8DPP9
SCHEMBL29874508 0.88 ACE (0.49) DPP4PREPFAPDPP8DPP9
SCHEMBL1046072 0.88 DPP4 (0.46) DPP4PREPFAPDPP8DPP9
SCHEMBL1046070 0.88 DPP4 (0.46) DPP4PREPFAPDPP8DPP9
SCHEMBL1402279 0.88 CHRM2 (0.42) DPP4PREPFAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024178352-A2 BMP SYNTHASE ACTIVATORS AND INHIBITORS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-08-29 WO claimed
US-20230374112-A1 Bioactive Collagen Peptides, Method Of Production Thereof, And Use Thereof BDC CAPITAL INC. (CA) 2023-11-23 US claimed
WO-2022067445-A1 BIOACTIVE COLLAGEN PEPTIDES, METHOD OF PRODUCTION THEREOF, AND USE THEREOF CORPORATION GENACOL CANADA INC. (CA) 2022-04-07 WO claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2026-04-02 US disclosed
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2025-12-18 US disclosed
US-20250382360-A1 Anti-VEGF Single Chain Variable Fusion Protein (RNAT82) MAGOOLA MATTHIAS (UG) 2025-12-18 US disclosed
US-20250381288-A1 Anti-VEGF Single Chain Variable Fusion Protein (RNAT92) NIAZI SARFARAZ K (US) 2025-12-18 US disclosed
US-20250381287-A1 Anti-VEGF Fusion Protein (RNAT53) NIAZI SARFARAZ K (US) 2025-12-18 US disclosed
EP-4608437-A2 COMBINATION TREATMENT REGIMES FOR TREATING CANCER Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 EP disclosed
EP-4608455-A1 SELF-ASSEMBLING NANOPARTICLES Barinthus Biotherapeutics North America, Inc. (US) 2025-09-03 EP disclosed
WO-2022139539-A1 COMPOSITION FOR PREVENTION OR TREATMENT OF SARS-COV-2 INFECTION 아주대학교산학협력단 2022-06-30 WO disclosed
US-20220143130-A1 Peptides Having Immunomodulatory Properties Riptide Bioscience, Inc. 2022-05-12 US disclosed
EP-3206704-B1 PEPTIDES HAVING ANTI-INFLAMMATORY PROPERTIES RIPTIDE BIOSCIENCE INC (US) 2022-04-20 EP disclosed
WO-2022067445-A1 BIOACTIVE COLLAGEN PEPTIDES, METHOD OF PRODUCTION THEREOF, AND USE THEREOF CORPORATION GENACOL CANADA INC. (CA) 2022-04-07 WO disclosed
EP-0545991-B1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF VAHLNE ANDERS (SE) 1998-12-02 EP disclosed
EP-0545991-B1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF VAHLNE ANDERS (SE) 1998-12-02 EP disclosed
US-5627035-A Peptides that block human immunodeficiency virus and methods of use thereof SYNTELLO VACCINE DEVELOPMENT AB (SE) 1997-05-06 US disclosed
EP-0545991-A1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF VAHLNE, Anders (SE) 1993-06-16 EP disclosed
WO-1992003147-A1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF SYNTELLO VACCIN DEVELOPMENT KB (SE) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER IL2, IFNG, ICOS DPP4 2639/4885PREP 914/4885FAP 1715/4885
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP DPP4 43/4885PREP 4/4885FAP 165/4885
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES VIP, HM13, SPPL2B DPP4 1168/4885PREP 230/4885FAP 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.