Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566029 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL4673678 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL844128 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL844722 | 0.87 | LMNA (0.51) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL6631278 | 0.87 | LMNA (0.51) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL4533970 | 0.84 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL7291562 | 0.84 | LMNA (0.55) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL7459001 | 0.84 | LMNA (0.55) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL5453145 | 0.84 | LMNA (0.55) | LMNASMN1; SMN2HTTMAPTALDH1A1 | |
| SCHEMBL1713427 | 0.84 | LMNA (0.55) | LMNASMN1; SMN2HTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559752-B1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5364861-A | Bactericides with side effect reduction | WARNER-LAMBERT COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| US-5278317-A | Aminomethylpyrrole | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0559752-A1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5157128-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| WO-1992009597-A1 | OPTICAL ISOMERS OF 7-[3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5072001-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1991-12-10 | — | — | US | disclosed |