Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796572 | 0.80 | EGLN3 (0.49) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL7618324 | 0.78 | MEN1 (0.58) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL5089332 | 0.74 | MEN1 (0.54) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL17329321 | 0.74 | HSD17B10 (0.50) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL3867305 | 0.72 | HPGD (0.60) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL24942737 | 0.72 | MEN1 (0.64) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL630931 | 0.72 | MEN1 (0.64) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL16740930 | 0.71 | MEN1 (0.54) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL14740086 | 0.71 | HSD17B10 (0.54) | HPGDHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL7855409 | 0.71 | MEN1 (0.54) | HPGDHSD17B10MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |