Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560752 | 0.90 | LPAR1 (0.47) | LPAR1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8560596 | 0.85 | LPAR1 (0.47) | LPAR1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8566775 | 0.85 | LPAR1 (0.47) | LPAR1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8567301 | 0.85 | LPAR1 (0.47) | LPAR1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8567545 | 0.83 | MAPT (0.42) | LPAR1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8566120 | 0.80 | MAPT (0.42) | LPAR1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8557914 | 0.79 | KMT2A (0.45) | LPAR1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8557908 | 0.79 | KMT2A (0.45) | LPAR1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4118333 | 0.79 | LPAR1 (0.53) | LPAR1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL5520431 | 0.75 | MEN1 (0.49) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770438-A | CHEMICAL INTERMEDIATES FOR ANTICHOLESTEROL COMPOUNDS, CYCLIZATION TO FORM BENZOXAZEPINE OR BENZOTHIAZEPINE COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0710725-A1 | Production of optically active compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |