SCHEMBL8565128

SCHEMBL8565128

CCCCC/C=C(/C)C(=O)O.[NaH].[NaH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.61
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
TERT O14746 3/20 0.44
PTPN1 P18031 3/20 0.44
PPARG P37231 3/20 0.44
PPARD Q03181 3/20 0.44
PPARA Q07869 3/20 0.44
TOP1 P11387 3/20 0.44
MAPT P10636 2/20 0.44
BLM P54132 2/20 0.44
HSD17B10 Q99714 2/20 0.44
FABP4 P15090 2/20 0.44
GMNN O75496 1/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7358659 1.00 EP300 (0.61) EP300FNTAFNTBTERTPTPN1
SCHEMBL27342580 1.00 EP300 (0.61) EP300FNTAFNTBTERTPTPN1
SCHEMBL7358668 1.00 EP300 (0.61) EP300FNTAFNTBTERTPTPN1
Water SCHEMBL27859006 0.98 EP300 (0.59) EP300FNTAFNTBTERTPTPN1
SCHEMBL21568 0.98 EP300 (0.63) EP300FNTAFNTBTERTPTPN1
SCHEMBL1126330 0.98 EP300 (0.63) EP300FNTAFNTBTERTPTPN1
SCHEMBL21570 0.98 EP300 (0.63) EP300FNTAFNTBTERTPTPN1
SCHEMBL22151496 0.96 EP300 (0.67) EP300FNTAFNTBTERTPTPN1
SCHEMBL22151498 0.96 EP300 (0.67) EP300FNTAFNTBTERTPTPN1
Iodide SCHEMBL7871722 0.96 EP300 (0.61) EP300FNTAFNTBTERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107095874-B A kind of pediatric pharmaceuticals compositions and preparation 广东金城金素制药有限公司 2018-07-03 CN claimed
CN-101418015-B Ceftriaxone phosphorylation derivates SHANDONG XUANZHU PHARM TECH CO 2011-04-27 CN claimed
CN-101475913-A Special culture medium for separating phytophthora sojae UNIV NORTHEAST AGRICULTURAL (CN) 2009-07-08 CN claimed
CN-101418015-A Ceftriaxone phosphorylation derivates SHANDONG XUANZHU PHARM TECH CO (CN) 2009-04-29 CN claimed
CN-1158120-A Process for the preparation of antimicrobial compounds PROCTER & GAMBLE (US) 1997-08-27 CN claimed
CN-118290442-A Preparation method of decarboxylated Larox cephalosporin 重庆吉斯瑞制药有限责任公司 2024-07-05 CN disclosed
CN-116836182-A Integral recovery method of active ingredients in ceftriaxone sodium crystal acetone mother liquor 国药集团威奇达药业有限公司 2023-10-03 CN disclosed
CN-115581700-A Pharmaceutical composition containing cefotaxime sulbactam or cefotaxime tazobactam with stable quality and high antibacterial activity 湘北威尔曼制药股份有限公司 2023-01-10 CN disclosed
CN-113194943-B Pharmaceutical composition containing cefotaxime sulbactam or cefotaxime tazobactam with stability and antibacterial activity 广州新创忆药物临床研究有限公司 2022-11-25 CN disclosed
CN-111072497-B Method for recovering N, N' -dibenzylethylenediamine salt from ion exchange resin to be regenerated of cefonicid sodium 华北制药河北华民药业有限责任公司 2022-10-25 CN disclosed
CN-112679524-B Preparation method of ceftriaxone sodium 华北制药河北华民药业有限责任公司 2022-07-01 CN disclosed
CN-114634423-A Method for continuously recovering acetonitrile from acetonitrile mother liquor generated in 7-ACT synthesis 国药集团威奇达药业有限公司 2022-06-17 CN disclosed
CN-1046524-C Cephalosporin derivatives HOFFMANN LA ROCHE (CH) 1999-11-17 CN disclosed
US-5804577-A ANTIBIOTICS HOFFMANN-LA ROCHE INC. (US) 1998-09-08 US disclosed
CN-1181382-A Vinylpyrrolidinon cephalosporin derivatives HOFFMANN LA ROCHE (CH) 1998-05-13 CN disclosed
US-5672600-A Antimicrobial dithiocarbamoyl quinolones THE PROCTER & GAMBLE COMPANY (US) 1997-09-30 US disclosed
CN-1158120-A Process for the preparation of antimicrobial compounds PROCTER & GAMBLE (US) 1997-08-27 CN disclosed
CN-1105365-A Cephalosporin derivatives HOFFMANN LA ROCHE (CH) 1995-07-19 CN disclosed
CN-1028236-C Process for preparing acyl derivatives HOFFMANN LA ROCHE (CH) 1995-04-19 CN disclosed
CN-1036958-A The preparation method of acyl derivative HOFFMANN LA ROCHE (CH) 1989-11-08 CN disclosed