SCHEMBL1126330

SCHEMBL1126330

CCCCC/C=C(/C)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.63
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
TOP1 P11387 3/20 0.45
MAPT P10636 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
CYP2C9 P11712 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21570 1.00 EP300 (0.63) EP300FNTAFNTBTERTPTPN1
SCHEMBL21568 1.00 EP300 (0.63) EP300FNTAFNTBTERTPTPN1
SCHEMBL166403 0.98 EP300 (0.67) EP300FNTAFNTBTERTPTPN1
Hydrochloric Acid SCHEMBL7866780 0.98 EP300 (0.61) EP300FNTAFNTBTERTPTPN1
SCHEMBL456574 0.98 EP300 (0.67) EP300FNTAFNTBTERTPTPN1
SCHEMBL8565128 0.98 EP300 (0.61) EP300FNTAFNTBTERTPTPN1
SCHEMBL22151498 0.98 EP300 (0.67) EP300FNTAFNTBTERTPTPN1
SCHEMBL22151482 0.98 EP300 (0.67) EP300FNTAFNTBTERTPTPN1
SCHEMBL22151487 0.98 EP300 (0.67) EP300FNTAFNTBTERTPTPN1
Iodide SCHEMBL7871722 0.98 EP300 (0.61) EP300FNTAFNTBTERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186116-B Preparation method of cefvicin intermediate 浙江荣耀生物科技股份有限公司 2024-06-07 CN claimed
CN-117186116-A Preparation method of cefvicin intermediate 浙江荣耀生物科技股份有限公司 2023-12-08 CN claimed
CN-116783203-A Preparation method of high-yield and high-purity flomoxef UK化学药剂有限公司 2023-09-19 CN claimed
CN-116731039-A Process for the preparation of cephalosporin derivatives 重庆汉佩生物科技有限公司 2023-09-12 CN claimed
EP-3626721-B1 SYNTHESIS OF ESTER AND AMIDE DERIVATIVES OF BETA-LACTAM NUCLEI BONOMI PAOLO (FR) 2023-09-06 EP claimed
CN-116514841-A Preparation method of flomoxef acid impurity 福建省福抗药业股份有限公司 2023-08-01 CN claimed
CN-115791996-A Analysis and detection method of cefcapene pivoxil hydrochloride intermediate cefcapene precursor acid 凌晟(武汉)生物医药技术有限公司 2023-03-14 CN claimed
CN-113398072-B Cefazolin sodium for injection and preparation method thereof 广东金城金素制药有限公司 2023-03-07 CN claimed
CN-114401970-A Siderophore cephalosporin conjugates and uses thereof 纳布里瓦治疗有限责任公司 2022-04-26 CN claimed
CN-111171051-B Preparation method of cefixime 山西阳和医药技术有限公司 2021-09-10 CN claimed
CN-1120045-A New cephalosporins containing in position 7 a substituted benzyloxyimino radical, their preparation process, their use as medicaments ROUSSEL UCLAF (FR) 1996-04-10 CN claimed
CN-1028236-C Process for preparing acyl derivatives HOFFMANN LA ROCHE (CH) 1995-04-19 CN claimed
CN-1073177-A Novel cephalosporins containing a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1993-06-16 CN claimed
CN-1021226-C PREPARATION FOR ACYL DERIVATIVES HOFFMANN LA ROCHE (CH) 1993-06-16 CN claimed
CN-1036958-A The preparation method of acyl derivative HOFFMANN LA ROCHE (CH) 1989-11-08 CN claimed
CN-87105204-A ACYL DERIVATIVES 1988-06-29 CN claimed
CN-86105905-A Process for the preparation of cephalosporin nucleus derivatives and their use in medicaments 1987-07-29 CN claimed
US-4476124-A ISOCEPHALOSPORIN ANTIBIOTICS ROUSSEL UCLAF (FR) 1984-10-09 US claimed
US-4097670-A ANTIBIOTICS E. R. SQUIBB & SONS, INC. (US) 1978-06-27 US claimed
US-4028354-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1977-06-07 US claimed